Introduction: Tribulus is a flowery plant, which relates with the family of Zygophyllaceae. It is also known as puncture wine, caltrop, yellow wine and gaothead. It can survive in warm temperature zones, having poor soil conditions. It grows up to a length of 90 cm. It contains small- yellow flowers & five angled, spiny fruits. It is used as a chief Ayurvedic tonic ingredient and known as 'Gokshura' in Sanskrit language in India. Tribulus is an effective herb for improving sex capability.

Tribulus is natural herb, which is mainly known for improving athletic performances and stamina sexual activities. It is also consumed for building size of muscles. To get these benefits, athletics and body builders consume this medicine. However, like other medicines, tribulus also requires a balanced diet, regular & proper exercise and complete rest as required by a human body. The suggested amount of tribulus is between 85 to 250 mg with meals thrice a day. A person could vary the amount of its dosage according with the purpose for which it is taking. The excess quantity can create many side effects of tribulus on human body.

Tribulus is assumed as a toxic substance in nature and can cause unrelieved, progressive, and irreversible damage to the dopamine circuits of the brain. One of the other side effects of tribulus is that it promotes weakness in bones & hindquarters, and problem in movements of muscles. In severe cases, it also leads a person to sudden death. This is strictly prohibited medicine for children and pregnant women. The excess intake or consuming without proper consultation can raise many negative effects on human body. Mainly on those who suffers from various health diseases such as diabetes, high blood pressure, high cholesterol, asthma, infection in kidneys, and cancer of any body part.

It is necessary to take proper and correct advice from medical expert or doctor. The doctor, to whom a consumer is consulting, should be an experienced practitioner. Only an expert can suggest about the proper amount dosage and positive and negative effects of its intake. The medicine made with this herb can give a severe negative effect human body, if taken without doctor's supervision. The side effects of tribulus are normally common in each person, who is suffering from its negative outcome.

There is one more tribulus named as Bulgarian tribulus. This also grows in hot temperate regions, which have poor soil conditions & low availability of water. This is a famous medicine in the field of bodybuilding and for those, who are interested in weight training. This herb also has some negative side effects like diarrhea, which caused at beginning of consumption. In few cases, people complaints about upset stomach and over-growth of testosterone hormone in body. This hormone causes the unwanted growth of hairs on body and face, mood swings that generally results in anger and changes in voice. Those who are working on modern researches on Bulgarian tribulus have not discovered any negative side effect of this herb. On the same time, benefits are also not noticed by this herb.